Extended Data Fig. 4: Compositions and functions of T and B lymphocytes contributes to the pathogenesis of eCRSwNP.
From: Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis
a, tSNE plots showing expression of marker genes for generalized T cell subsets defined in Fig. 3a. b, Violin plots of the expression levels of selected genes in CD8+ TRM among control and CRS subtypes (MAST with RE adjusted by Benjamini–Hochberg procedure; full list of P value given in Supplementary Table 4; full list of P value given in Supplementary Table 4). c, tSNE plots showing expression of marker genes for B cell subsets defined in Fig. 3e. d, Box and whisker plots showing the fraction of B lymphocytes originating from 4 groups (5 healthy controls, 5 CRSsNP, 5 neCRSwNP, and 6 eCRSwNP patients) in each cluster, with plot center, box and whiskers corresponding to median, IQR and 1.5 × IQR, respectively (MASC adjusted by Benjamini–Hochberg procedure; *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001; Supplementary Table 2). This figure supports Fig. 3.
