Extended Data Fig. 1: Functional characterization of the epithelial cells in control and CRS patients.
From: Single-cell profiling identifies mechanisms of inflammatory heterogeneity in chronic rhinosinusitis
a, tSNE plots showing expression of marker genes for all 8 major cell types defined in Fig. 1b. b, tSNE plots showing expression of marker genes for epithelial subsets defined in Fig. 2a. c, Heatmaps of PAGA graph displaying the evolving expression pattern of key genes in four developing pathways of epithelial cells in Fig. 2d. d, Heatmap of the enriched GO biological processes terms among the different epithelial clusters (full list of P value adjusted by Benjamini–Hochberg procedure given in Supplementary Table 5). e, Violin plots of the proliferation score of epithelial subsets with plot center and box corresponding to median and IQR respectively. f-h, Violin plots of the expression levels of selected genes in goblet (f), ciliated (g) and glandular (h) subsets among control and CRS subtypes (MAST with RE adjusted by Benjamini–Hochberg procedure; full list of P value given in Supplementary Table 4). This figure supports Figs. 1, 2.
