Extended Data Fig. 7: Single cell identification of BCP-ALL CD34-expressing cluster throughout primary human BCP-ALL CAR-T therapy. | Nature Immunology

Extended Data Fig. 7: Single cell identification of BCP-ALL CD34-expressing cluster throughout primary human BCP-ALL CAR-T therapy.

From: NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia

Extended Data Fig. 7

(a) UMAP representation of primary BCP-ALL patient single cell dataset generated by Rabilloud et al. highlighting CD19dim and CD19pos cell clusters pre (T1) and post (T2) CAR-T cell therapy, with sample cluster CD19 and CD34 mRNA levels indicated. (b) Dot plot representation of cluster-specific mRNA expression levels from BCP-ALL CAR-T patient single cell data.

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