Extended Data Fig. 6: 6p21.3 loss in human cancers.
From: In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
a, Frequency of 6p21.3 deletion across TCGA histopathologies and their overall survival hazard ratios as calculated by Cox proportional hazard models. P-values are calculated from z-statistics. Data are presented as hazard coefficients and 95% confidence intervals. b, Kaplan-Meier plots of overall survival in the Braun patient cohort, stratified by 6p21.3 copy number status. c, Univariate Cox proportional hazard models for the Braun data set, calculated for the nivolumab treated patient cohort (n = 48 patients for 6p21.3 disomy and 46 patients for 6p21.3 deletion). P-values are calculated from z-statistics. Data are presented as hazard coefficients and 95% confidence intervals.
