Extended Data Fig. 2: Translatome analysis of microglia during the RR-EAE course. | Nature Immunology

Extended Data Fig. 2: Translatome analysis of microglia during the RR-EAE course.

From: Cognate microglia–T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology

Extended Data Fig. 2

(a) Representative genes from each cluster. Light gray circles, input, dark gray triangles, IP IgG, light blue squares, IP HA. Each dot represents individual mice, lines represent mean. NI, non-immunized, INIT, initiation, MAX, maximal score, REM, remission, RCOV, clinical recovery, REL, relapse. N = 6 NI, 4 INIT, 6 MAX, 8 REM, 5 RCOV and 4 REL individual mice per group. (b) Expression of selected genes encoding proposed BAM markers during the RR-EAE course. Heatmap represents log2 values of average HA samples in each stage, alongside graphs of expression of individual genes. N = 6 NI, 4 INIT, 6 MAX, 8 REM, 5 RCOV and 4 REL individual mice per group, lines represent mean.

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