Extended Data Fig. 9: Analysis of engrafted MOG-specific TCR transgenic cells (2D2). | Nature Immunology

Extended Data Fig. 9: Analysis of engrafted MOG-specific TCR transgenic cells (2D2).

From: Cognate microglia–T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology

Extended Data Fig. 9

(a) Workflow and gating strategy for concatenation of 2D2 cells. Related to Fig. 8h. (b) Flow cytometric analysis of brains of three representative individual control and MgΔMHCII mice to show the reporter gene expression in the 2D2 graft. (c) Gates used for concatenation shown in Fig. 8h. Upper plots represent entire 2D2 concatenated population, lower plots represent only Foxp3+ cells gated from 2D2+ cells, in control (left) or MgΔMHCII (right). Related to Fig. 8h.

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