Fig. 6: Local histological and immune response heterogeneity following Treg cell depletion.
a, H&E staining of representative tumor section characterized by histological and immune response state heterogeneity after Treg cell depletion. Insets at bottom represent a zoomed-in view of gastric (left) and high-plasticity (right) areas. Black arrows highlight neutrophil infiltration in a high-plasticity area. b, Tumor RNA fraction within highlighted high-plasticity and gastric epithelial states (left) and gene expression modules (right) of tumor lesion shown in a. Images are representative of one of two serial sections for each of four samples (DT and Ctrl, two biological replicates each).
