Extended Data Fig. 7: Human dietary intervention study.
From: Short-term dietary changes can result in mucosal and systemic immune depression
(a) Schematic showing the human dietary intervention study. (b) PCA of stools isolated from each volunteer at the end of each dietary interventions. (c) Representative dot plots of human PBMCs gated on viable CD3− cells showing specificity of IFN-γ and IL-17A staining. (d) Representative dot plots of unstimulated and stimulated (with and without FMOs for anti-IFN-γ-BV786 and anti-IL17A-BV421) human PBMCs gated on viable CD3+CD4+ cells. (e) PCA of stools isolated from GF mice after being colonized with FRD or FPD-human stools. Three volunteers used are shown. Each dot represents one GF mouse; 3 GF mice per volunteer per time-point were used.
