Extended Data Fig. 2: Comparative analysis of T cell subset definitions across individual modalities. | Nature Immunology

Extended Data Fig. 2: Comparative analysis of T cell subset definitions across individual modalities.

From: Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment

Extended Data Fig. 2

(a) Overview of single-cell labeling methods used for each TEA-seq modality (ADT, RNA, or ATAC). (b) Confusion plot comparison of T cell subset labels of single T cells between ADT-defined and Seurat RNA-prediction methods. (c) Confusion plot comparison of T cell subset labels of single T cells between ADT-defined and ATAC-prediction (ArchR) methods. (d) Confusion plot comparison of WNN labels and RNA-based label transfer of ADT-defined (CD45RA+CD197+CD27+) naive CD4 T cells.

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