Extended Data Fig. 4: Both CD47 and SIRPα inhibit FcR-mediated tumor growth.
From: CD47 masks pro-phagocytic ligands in cis on tumor cells to suppress antitumor immunity
Tumors from the experiment depicted in Fig. 3d were dissected, weighed, measured and analysed by flow cytometry. One mouse from ‘Rag1-/- mice + Ctrl IgG (C1.18.4)’ group showed no clinically detectable tumor on day 18. All data are means ± s.e.m. ns, not significant; ****p < 0.0001. Results are pooled from a total of 15 mice [16 mice for ‘Rag1-/- mice + Tac mAb (7G7)’ group] from 3 independent experiments. Each symbol represents one mouse.
