Extended Data Fig. 2: Characteristics of the MPXV A35 ectodomain proteins.
From: Rational design of a ‘two-in-one’ immunogen DAM drives potent immune response against mpox virus
(a–g) Analytical ultracentrifugation analysis (A35Ecto (a), A35ΔDB (b) and A35scDimer (c), A35Ecto-ΔC62 (d), A35Ecto-ΔC62A (e)) and analytical gel filtration profiles (A35Ecto-ΔC62 (f), A35Ecto-ΔC62A (g)) of the MPXV A35 ectodomain proteins were shown. Sedimentation coefficient distributions c(s) calculated from the sedimentation velocity profile with the calculated molecular weight (Mf) shown. The SDS-PAGE analyses were repeated three times. (h) The specific IgG titers elicited by the MPXV A35 ectodomain proteins (n = 5). Data indicate mean ± s.d. P values were determined by one-way ANOVA with multiple comparison tests. ns, P > 0.05.
