Extended Data Fig. 6: Sensitivity analysis of PASC symptom group differences.
a, Age matching of symptom groups upon exclusion of individuals <30 years of age. P-value derived from two-sided t-test. b, Results from re-analysis of clinical parameters using a two-sided Wilcoxon test applied to the age-matched PS and NPS groups shown in a. Black asterisks represent significance at p-value.p<0.1, *p<0.05, **p<0.005. c, Test of symptom group effect using a linear model applied to log2 transformed parameters with correction for acute disease severity group (group B-E). P-value thresholds as in b. d, Re-analysis of clinical parameters by two-sided Wilxocon test in age and acute disease severity matched PS and NPS groups. Age and severity matching is shown in e, p-value thresholds as in b. f, Patient-level findings for iron and inflammatory parameters shown in d. Timepoints of interest are indicated with red arrows. Patients are colored by acute disease severity. Boxplots show minimum, 25th percentile, median, 75th percentile and maximum, and outliers beyond 1.5 times the interquartile range. PS = persisting symptom, NPS = no persisting symptoms.
