Extended Data Fig. 8: IL-12 and IFNγ DEG are enriched for TH1, Treg, and B cell proliferation genes. | Nature Immunology

Extended Data Fig. 8: IL-12 and IFNγ DEG are enriched for TH1, Treg, and B cell proliferation genes.

From: IL-12 induces a B cell-intrinsic IL-12/IFNγ feed-forward loop promoting extrafollicular B cell responses

Extended Data Fig. 8

Gene set enrichment analysis (GSEA) plots illustrating significant upregulation of TH1 Treg, and B cell proliferation related genes at 24 hours of IL-12 and IFNγ samples (n = 3) compared with their control conditions. The FDR adjusted P values (FDR) indicated in each chart were calculated using rankSumTestWithCorrelation function from the R limma package.

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