Table 1 Breast cancer patient clinical information
From: Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity
Patient no. | Sample type | Na+ (g kg−1) | K+ (g kg−1) | Sex | Tumor status | Nodal status | Metastasis | Grading | Stage according to UICC | Estrogen receptor (%) | Progesterone receptor (%) | Her2 status | Histological classification | Localization of breast tumor | Neoadjuvant therapy |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Lesional tumor | 2.18 | 3.34 | F | pT1c, pTis (DCIS, non-high-grade with necrosis—intermediate malign) | pN0 (sn), (0/2) | MX | G2 | IV | 100 | 90 | 2+ (FISH negative) | Ductal | Right | No |
2 | Perilesional tissue | 3.22 | 1.89 | ||||||||||||
3 | Lesional tumor | 4.98 | 4.27 | F | pT1c (m), pTis | pN1a (1/13) | cM0 | G2 | IIA | 95 | 70 | Negative (DAKO-score 1+) | Lobular | Left | No |
4 | Perilesional tissue | 0.735 | 0.337 | ||||||||||||
5 | Lesional tumor | 9.34 | 4.49 | F | pT4b | pN2a (8/10) | MX | G1 | IV | 90 | 2+ (positiv). | Ductal | Left | No | |
6 | Perilesional tissue | 2.46 | 0.905 | ||||||||||||
7 | Lesional tumor | 4.74 | 6.18 | F | pT1c | pN(sn)0 (0/2) | MX | G2, BRE-score: 6 (2 + 1 + 3) | IV | 100 | 2 | 2+ (FISH negative) | Ductal | Left | No |
8 | Perilesional tissue | 2.76 | 0.978 | ||||||||||||
9 | Lesional tumor | 8.52 | 2.21 | F | pT1c | pN(sn)0 (0/3) | MX | G1 | IV | 10 | 100 | 2+ (FISH negative) | Mucinous | Left | No |
10 | Perilesional tissue | 0.464 | 0.207 | ||||||||||||
11 | Lesional tumor | 6.54 | 11.7 | F | pT2 | pN1 (1/9) | MX | G2, BRE-score: 7 (1 + 3 + 3) | IV | 100 | 70 | Negative | Ductal | Right | No |
12 | Perilesional tissue | ||||||||||||||
13 | Lesional tumor | 6.04 | 9.08 | F | pT2 | pN0 (sn) (0/2) | MX | G2 | IV | 100 | 95 | Negative (score 1+) | Ductal | Right | No |
14 | Perilesional tissue | 1.74 | 0.91 | ||||||||||||
15 | Lesional tumor | 6.25 | 10 | F | pT1c | pN(sn)0 (0/2) | cM0 | G3, BRE-score 9 | I | Negative | Negative | 2+ (FISH negative) | Ductal | Left | No |
16 | Perilesional tissue | 1.96 | 0.823 | ||||||||||||
17 | Lesional tumor | 5.69 | 11.7 | F | pT1c(m), pTis | pN0sn (0/5) | cM0 | G2 (invasive component), WHO grade II (DCIS) | I | 90% positive in the invasive carcinoma, 90% in the in situ component | Positive (80%) invasive carcinoma, 20% in situ component | 2+ (FISH negative) | Ductal | Left | No |
18 | Perilesional tissue | 8.63 | 4.07 | ||||||||||||
19 | Lesional tumor | 7.32 | 7.83 | F | pT4b | pN2a (7/7) | MX | G3, BRE-score: 8 (3 + 3 + 2) | IV | Negative | Negative | 2+ (FISH negative) | Ductal | Right | No |
20 | Perilesional tissue | 4.52 | 1.32 |
