Extended Data Fig. 2: scRNA-seq result analyses of LLC tumors in WT and Pcif1 KO mice. | Nature Immunology

Extended Data Fig. 2: scRNA-seq result analyses of LLC tumors in WT and Pcif1 KO mice.

From: The epitranscriptional factor PCIF1 orchestrates CD8+ T cell ferroptosis and activation to control antitumor immunity

Extended Data Fig. 2

a, Uniform Manifold Approximation and Projection (UMAP) showing 20 clusters of total cells from LLC tumors carried subcutaneously in WT or Pcif1 KO mice (n = 2 mice/each group). b, Heat map from scRNA-seq displaying normalized expression of selected genes in each cluster. c-i, Dot plot showing the expression of representative genes for each cell type (c). And the UMAP displays six clusters of total cells (d) and marker genes (e-i). j, UMAP plot showing secondary clusters of lymphoid cells. k, Heat map from scRNA-seq displaying normalized expression of selected genes in each cluster. l-r, Dot plot (l) and UMAP plots (m-r) showing the expression of selected marker genes for each cell type.

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