Extended Data Fig. 1: NAT10 helps to maintain the pool of T cells.
a tSNE visualization of splenic and thymic single cells from FLOX and CKO mice by clusters. b Table listing the exact percentage of cells from FLOX or CKO mice as a fraction of total T cells for each cluster, corresponding to the bar plot in Fig. 2e. c UMAP visualization of splenic T cells from FLOX and CKO mice identified in Fig. 2d. d Bar plot showing the percentage of cells from FLOX or CKO mice as a fraction of total T cells for each cluster, related to the UMAP plot in (c). e Bubble plot exhibiting the top 8 up-regulated (left) and 10 down-regulated (right) transcripts of CKO versus FLOX splenic T cells. Populations marked by blue and red block represent T cells from FLOX and CKO mice, respectively. f Bar graph showing the geometric mean fluorescence intensity (MFI) of CD8α and CD8β1 in FLOX and CKO CD8+T cells. Error bars represent mean ± s.e.m. n = 3 biologically independent samples. **P = 0.0065, *P = 0.0112. Two-tailed, unpaired t-test.
