Addendum to: Nature Immunology https://doi.org/10.1038/ni852, published online 4 November 2002.
Concerning the original publication, the authors acknowledge and apologize for possible inadvertent errors that may have occurred during the assembly of PCR measurements for β-actin expression in Langerhans cells and monocytes, as well as CCL2/7 expression in UV-irradiated skin. Unfortunately, the original data were generated over 22 years ago and are no longer available. However, Langerhans cells and monocytes express β-actin and the reproducibility of UV-induced CCL2 and CCL7 expression is validated through immunohistochemistry (Fig. 6b in original article) and corroborated by multiple independent studies in mice and human.
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Merad, M., Manz, M.G., Karsunky, H. et al. Addendum: Langerhans cells renew in the skin throughout life under steady-state conditions. Nat Immunol 26, 805 (2025). https://doi.org/10.1038/s41590-025-02131-9
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DOI: https://doi.org/10.1038/s41590-025-02131-9