Extended Data Fig. 8: LPAM distribution in Cx3cr1^GFP/+Flt3l^−/− mice and MHCII expression in different LPAMs.

(a) The 3D confocal imaging of the mouse liver lobe from Cx3cr1^GFP/+Flt3l^−/− mice. Scale bar, 2000 μm. The imaging data were from representative experiments. (b) Calculate the percentage of MHC-II expression in CD45.1⁺ LPAMs (blood-borne) and CD45.2⁺ LPAMs (self-renewing) in CD45.2 mice. The data were pooled from three independent experiments, mean ± SD, n = 3 mice per group; two-tailed unpaired t-test.

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