Table 1 Locations and methylation of the most strongly hypomethylated HERVIP10F-int and LTR45B insertion sites overlapping with DMRs hypomethylated in skin Treg cells

From: DNA hypomethylation traits define human regulatory T cells in cutaneous tissue and identify their blood recirculating counterparts

Chr.

Interval

Meth. blood RA+ Treg cells

Meth. skin Treg cells

Meth. diff.

HERVIP10F-int

 4

141519736–141521252

0.860

0.477

−0.383

 11

92994750–92995433

0.828

0.542

−0.370

 14

21193203–21193472

0.903

0.542

−0.361

 2

132899525–132902896

0.857

0.505

−0.352

 11

67456726–67457160

0.749

0.400

−0.349

LTR45B

 4

107573927–107573965

1.000

0.254

−0.746

 10

33423433–33423859

0.664

0.100

−0.564

 12

106417286–106417799

0.758

0.200

−0.558

 20

13999437–13999668

0.719

0.167

−0.552

 11

5612894–5613203

0.792

0.317

−0.475

  1. Methylation values correspond to the mean across three donors (Tissue Donors 7, 10 and 11 and Blood Donors 3–5). Chr.; chromosome; Diff., difference; Meth., Methylation; RA, CD45RA.