Extended Data Fig. 7: Analysis of T cells in tumor-draining lymph node. | Nature Immunology

Extended Data Fig. 7: Analysis of T cells in tumor-draining lymph node.

From: Simultaneous STING and lymphotoxin-β receptor activation induces B cell responses in tertiary lymphoid structures to potentiate antitumor immunity

Extended Data Fig. 7

a, Upper panels: Live lymph node leukocytes were gated for CD3+ T cells, and the % fractions of total and activated CD8+ T cells in total CD3+ T cells were determined by flow cytometry. Lower panels: The numbers of total and activated CD8+ T cells in a draining lymph node were calculated from the total leukocyte count in each lymph node and the % fractions of the T cell subsets. For each data point, six draining lymph nodes were pooled and averaged. A total of 18 lymph nodes were examined for each group. A representative of two independent experiments is shown for each analysis. *p < 0.05; ***p < 0.01; **p < 0.001; ns, not significant. b, A similar analysis of CD4+ T cells in the draining lymph node. Upper panels: The % fractions of total and activated CD4+ T cells in total CD3+ T cells. Lower panels: The average numbers of total and activated CD4+ T cells in a draining lymph node.

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