Extended Data Fig. 8: Gene expression signature of enhanced immune responses upon combination therapy. | Nature Immunology

Extended Data Fig. 8: Gene expression signature of enhanced immune responses upon combination therapy.

From: Simultaneous STING and lymphotoxin-β receptor activation induces B cell responses in tertiary lymphoid structures to potentiate antitumor immunity

Extended Data Fig. 8

Bulk RNAseq was conducted using total RNA isolated from KPC tumors on the day of tumor resection (Day 14), and the data was processed by DEseq2. The graphs show the expression of different genes related to inflammation, innate immunity, and adaptive immunity in tumors of different treatment groups. One experiment. N = 8 tumors were examined representing biological replicates for each group. Data are presented as the mean ± s.e.m.

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