Extended Data Fig. 9: Gene expression patterns used to identify immune cell types in single-cell analysis. | Nature Immunology

Extended Data Fig. 9: Gene expression patterns used to identify immune cell types in single-cell analysis.

From: Simultaneous STING and lymphotoxin-β receptor activation induces B cell responses in tertiary lymphoid structures to potentiate antitumor immunity

Extended Data Fig. 9

a, The immune cell types identified in the UMAP clusters shown in Fig. 7 were determined based on the signature gene expression for each cell type. The genes listed here were found among the top 20 genes in each cluster using FindMarkers function of the Seurat application. b, Single-cell analysis of B cell subsets. Feature plots with module score for B cell subsets generated from the single-cell RNAseq analysis of tumor-infiltrating CD45+ cells on Day 14. Each B cell subset (follicular B, memory B, plasma cell, or long-lived plasma cell) was identified according to indicated marker genes. PC, plasma cell.

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