Extended Data Fig. 5: Disease-adapted and disease-specific fibroblast additional data. | Nature Immunology

Extended Data Fig. 5: Disease-adapted and disease-specific fibroblast additional data.

From: A single-cell and spatial genomics atlas of human skin fibroblasts reveals shared disease-related fibroblast subtypes across tissues

Extended Data Fig. 5

a) Dotplot of expression of marker genes used for healthy fibroblasts in lesional/diseased skin fibroblasts. b) Heatmap of genes that were used as marker genes for healthy fibroblasts but that were less specific when diseased fibroblasts were included. c) Gene set enrichment analysis for disease-associated fibroblast populations. d) Heatmap of gene expression for select collagens, common fibroblast activated genes, and additional markers for skin myofibroblasts. e) UMAP visualization of transcription factor activity scores (RUNX2, SCX).

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