Fig. 2: Skin fibroblasts occupy unique spatial and functional niches. | Nature Immunology

Fig. 2: Skin fibroblasts occupy unique spatial and functional niches.

From: A single-cell and spatial genomics atlas of human skin fibroblasts reveals shared disease-related fibroblast subtypes across tissues

Fig. 2

a, Spatial location of fibroblast subtypes in microenvironments (cell2location abundance predictions (10x Genomics Visium)) in a single section of healthy human skin (left). Histopathological annotation of tissue microenvironments (right). b, Spatial location of fibroblasts at single-cell resolution (10x Genomics Xenium 5000-gene panel) for skin sections from nonlesional skin of atopic dermatitis (noninflamed (left) and noninflamed post-treatment (right)), colored by cell type. c, Summary of fibroblast niches: Xenium cell types overlying H&E-stained image (manual approximations).

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