Extended Data Fig. 7: Sex differences in the antiviral antibody repertoire.
a, −log10(adjusted P-values) and direction of associations between all public peptide Z-scores and sex in the Milieu Intérieur cohort (two-sided Wald test). The dashed gray vertical lines indicate viruses for which the AVARDA breadth score is significantly associated with sex. The dashed red horizontal lines indicate the significance threshold (Padj < 0.05). b, −log10(adjusted P-values) against effect sizes for associations between the AVARDA breadth score and sex in the Milieu Intérieur cohort (two-sided Wald test). Each point indicates a virus, colored according to its viral family. c,d, −log10(adjusted P-values) against effect sizes for associations between (c) IAV and (d) IBV peptide Z-scores and sex in the Milieu Intérieur cohort, colored according to the viral protein (two-sided Wald test).
