Extended Data Fig 6: Foveal subcellular anatomy in four of the eight patients who had analyzable recordings at baseline and 3 months in both eyes. | Nature Medicine

Extended Data Fig 6: Foveal subcellular anatomy in four of the eight patients who had analyzable recordings at baseline and 3 months in both eyes.

From: Effect of an intravitreal antisense oligonucleotide on vision in Leber congenital amaurosis due to a photoreceptor cilium defect

Extended Data Fig 6

a,b, Longitudinal reflectivity profiles overlaid on foveal OCT scans showing signals associated with intraretinal anatomical features at baseline and month 3 in both eyes. c,d, Changes to outer retinal peaks in terms of backscatter intensity and the peaks used to measure inner (IS) and outer segment (OS) lengths proximal and distal to the connecting cilium, respectively. e,f, Bar graphs of the IS and OS length obtained from a single recording. na, not available due to foveal atrophy

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