Extended Data Fig. 2: Correlation between ISG core score and tumor purity in TCGA primary tumors.
From: Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss
a, Pearson correlation (R 2) between ISG core score and tumor purity (consensus purity estimate) in different lineages of TCGA primary tumors as indicated. Number of tumors for each lineage: BRCA, n = 1095; UCEC, n = 550; KIRC, n = 536; LUAD, n = 527; HNSC, n = 520; LGG, n = 520; LUSC, n = 501; THCA, n = 501; PRAD, n = 497; SKCM, n = 469; COAD, n = 467; OV, n = 422; BLCA, n = 410; LIHC, n = 372; CESC, n = 304; KIRP, n = 290; READ, n = 166; GBM, n = 163; ACC, n = 79; KICH, n = 66; UCS, n = 57. Each dot indicates a TCGA tumor sample. Dotted lines illustrate the score cutoff for ISG-high tumors. b, Number of TCGA primary tumors with respect to their purity status and ISG core scores.
