Extended Data Fig. 4: Examples of dilated lymphatic vessels induced by ARAF-S214P.
From: ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor
a, The construct used for transgene expression. b,c, ARAF-S214P expression (red) leads to dilation of the intersegmental lymphatic vessel (ISLV, b) and the parachordal line (PL, c). Scale bar, 200 μm.
