Extended Data Fig. 9: Overall study design.
From: Genome-wide association study of peripheral artery disease in the Million Veteran Program
The primary analysis consisted of a genome-wide association study to identify novel PAD risk variants. Secondary analyses involved a genome-wide association study of minimum ABI, a closer examination the 19 PAD risk variants through PheWAS, a candidate causal gene analysis using eQTL/pQTL/TWAS data, a PAD analysis accounting for CAD/LAS status and a focused Factor V Leiden analysis.
