Extended Data Fig. 1: Subject’s genealogy. | Nature Medicine

Extended Data Fig. 1: Subject’s genealogy.

From: Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report

Extended Data Fig. 1

Circles represent females, squares represent males, diamonds represent individuals whose gender has been masked for privacy, arrowhead depicts proband individual with MCI and shading indicates individual with history of dementia. Deceased individuals are marked with a crossed bar. APOE genotypes are indicated as appropriate to preserve anonymity. Family links were verified by three family informants. Genotypes of relatives of the R136S homozygote individual were determined by Sanger sequencing (Extended Data Fig. 2).

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