Extended Data Fig. 6: CSF cell count and IgG concentration in cases and controls do not explain EV signal by VirScan or ELISA.
From: Pan-viral serology implicates enteroviruses in acute flaccid myelitis
CSF enterovirus antibodies by VirScan a and ELISA are not correlated with the overall amount of CNS inflammation as measured by the CSF cell count (panel A) or CSF IgG (panel B) in a subset of patients. The 95% confidence intervals for each measurement are shaded in blue (ELISA) or red (Virscan). When comparing the concentration of IgG in a subset of AFM cases and OND controls, there was no difference in CSF IgG concentration (p = ns by Mann-Whitney, mean with errors bars showing standard deviation displayed). Two OND CSF IgG values were reported as < 0.9 mg/dL and were conservatively estimated to be 0. Errors bars represent 95% confidence intervals.
