Extended Data Fig. 1: Hierarchical clustering of HLA-I evolutionary divergences at individual HLA class I loci.
From: Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy
a, Hierarchical clustering of HED at HLA-A using all HLA-A alleles from all patient cohorts. b, Hierarchical clustering of HED at HLA-B using all HLA-B alleles. c, Hierarchical clustering of HED at HLA-C using all HLA-C alleles. Heat maps shows z-score normalized HED across all alleles. Color gradient of blue to red indicates low HED between allele pairs to high HED between allele pairs, respectively.
