Extended Data Fig. 8: COMPASS analysis of RV405. | Nature Medicine

Extended Data Fig. 8: COMPASS analysis of RV405.

From: Safety and immunogenicity of Ad26 and MVA vaccines in acutely treated HIV and effect on viral rebound after antiretroviral therapy interruption

Extended Data Fig. 8

COMPASS analysis of RV405. Heat map of posterior probabilities for RV405 data at the time of the peak cellular immune response post vaccination for A) HIV-1 Env specific CD4 T cells and CD8 T cells B) HIV-1 Gag specific CD4 T cells and CD8 T cells C) HIV-1 Pol specific CD4 T cells and CD8 T cells. Columns correspond to the functional cell subsets modelled by COMPASS, color coded by the type of function (white is not expressed while shaded is positive for that specific function). Responses are grouped by color and ordered by degree of functionality from one function on the left to five functions on the right. Rows correspond to subjects, which are ordered by their vaccine group. Each cell of the heat map shows the probability that the corresponding functional cell-subset exhibits an antigen-specific response and is color coded from white (zero) to purple (one).

Back to article page