Extended Data Fig. 1: Investigating goodness-of-fit by polygenic risk score deciles in FinnGen (n = 135,300). Y-axis represents the expected and observed risks in each decile.

Goodness-of-fit test for the Cox proportional hazards model with R package survMisc, following the methodology in May & Hosmer (2004).41 Error bars for the expected counts represent the 95% confidence intervals.