Extended Data Fig. 4: OA progression.
From: Articular cartilage regeneration by activated skeletal stem cells
a, Schematic of the experimental outline. Destabilization of the medial meniscus (DMM) was performed on adult mice, and the distal femurs were harvested after 8 weeks. Analysis was performed by IF, pentachrome, and Safranin-O Fast Green staining. b, Left, representative IF of indicated markers in sham and DMM joints. Scale bars 100μm. Right, Safranin-O Fast Green and pentachrome stains of sham and joints 8 weeks after DMM. Scale bars 500μm. (n = 3 per group). c, Quantification of IF stains in sham versus DMM. Graphs show mean + /- s.e.m. Two-tailed Student’s t-test. Exact P values to 2 significant figures. (n = 3 per group).
