Extended Data Fig. 2: Manhattan-like plot summarizing results from Cox proportional hazard models. | Nature Medicine

Extended Data Fig. 2: Manhattan-like plot summarizing results from Cox proportional hazard models.

From: Plasma metabolites to profile pathways in noncommunicable disease multimorbidity

Extended Data Fig. 2

Mirrored Manhattan-like plot showing the p-values from Cox proportional hazard models using metabolite levels as exposure and disease onset as outcome adjusting for age and sex. Colours indicate metabolite classes (see Fig. 1 in main text for a legend) and numbers on top indicate number of significantly associated metabolites (p < 4.93 × 10−5). Grey dots indicate associations not reaching significance. Positive associations are displayed in the upper panel and inverse associations in the lower. COPD=chronic obstructive pulmonary disease.

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