Extended Data Fig. 8: Evaluation of the diffusion of a viral vector from the PerMed to the heart.
From: A perfusable, multifunctional epicardial device improves cardiac function and tissue repair
a, Representative images of immunofluorescence staining for GFP and α-actinin 7 and 28 days after implantation of the PerMed in the BZ. b, Representative images of immunofluorescence staining for GFP and α-SMA 7 and 28 days after implantation of the PerMed in the border zone. c, Quantitative analysis of the expression of GFP by the ratio of the GFP area to the ROI area; n = 5 biologically independent samples per group. The data are expressed as mean ± s.d. NS indicates not significant. Data in (c) were analysed using a two-tailed Student’s t-test. AAV9: adeno-associated virus 9; GFP: green fluorescent protein; ROI: region of interest; BZ: border zone.
