Fig. 1: IgG(S-RBD) antibody response to mRNA SARS-CoV-2 vaccination in individuals with and without prior SARS-CoV-2 infection.
From: Antibody responses to the BNT162b2 mRNA vaccine in individuals previously infected with SARS-CoV-2

Box plots display the median values with the interquartile range (lower and upper hinge) and ±1.5-fold the interquartile range from the first and third quartile (lower and upper whiskers). We used two-sided Wilcoxon tests, without adjustment for multiple testing, to perform the following between-group comparisons: (1) infection-naive individuals (n = 903) and those with prior infection (n = 78), both at baseline (P < 0.001); (2) infection-naive individuals (n = 490) and those with prior infection (n = 35), both after dose 1 (P < 0.001); (3) infection-naive individuals (n = 228) and those with prior infection (n = 11), both after dose 2 (P < 0.001); (4) infection-naive individuals (n = 490) after dose 1 and those with prior infection (n = 78), both at baseline (P < 0.001); and (5) infection-naive individuals (n = 228) after dose 2 and those with prior infection (n = 35) after dose 1 (P = 0.92).