Extended Data Fig. 3: ACE2 Antibody Binding Capacity in Persons With and Without Prior SARS-CoV-2 infection: Values Above and Below 50%.
From: Antibody responses to the BNT162b2 mRNA vaccine in individuals previously infected with SARS-CoV-2
Box plots display the median values with the interquartile range (lower and upper hinge) and ±1.5-fold the interquartile range from the first and third quartile (lower and upper whiskers). Colors denote values above and below the 50% neutralizing threshold. We used two-sided Wilcoxon tests, without adjustment for multiple testing, to conduct the following between-group comparisons: (1) infection naïve (n = 490) and those with prior infection (n = 35), both following dose 1 (P < 0.001); (2) infection naïve (n = 228) and those with prior infection (n = 11), both following dose 2 (P = 1.00); and, (3) infection naïve (n = 228) following dose 2 and those with prior infection (n = 35) following dose 1 (P = 0.52).
