Extended Data Fig. 3: Overview of cellular immune profiles in COVID-19 patients.
From: Delayed production of neutralizing antibodies correlates with fatal COVID-19
a,b, Immune cell subsets of interest, plotted as a percentage of a parent population as (a) aggregate and (b) continuously over time according to the days of symptom onset for discharged or deceased patients. a, Immune cell subsets comparison in discharged or deceased patients. Negative controls (HCWs) are shown in black. Each dot represents a single individual at its maximum antibody titer over the disease course. Grey bars indicate mean values. ANOVA corrected for multiple comparisons using Tukey’s were used to determine significance. b, Longitudinal data plotted over time continuously. Regression lines are shown as light blue (discharged) and purple (deceased) and indicate cross-sectional averages from each group with shading representing 95% CI and are coloured accordingly. (HCW, n = 49; Discharged, n = 118; Deceased, n = 15). CD4Tfh, follicular helper T cells. ASC, antibody secreting cells. US, unswitched. CS, class switched.
