Fig. 2: Solicited local and systemic AEs 7 d after the first or second vaccine dose.
From: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19

Participants were monitored for solicited local (a) and systemic (b) AEs from the time of vaccination through 7 d after vaccine administration. There was no grade 4 (potentially life-threatening) event. Participants who reported no AEs make up the remainder of the 100% calculation (data not shown). If any of the solicited AEs persisted beyond Day 7 after each vaccination (when applicable), it was recorded as an unsolicited AE. Fever was defined as oral temperature ≥38.0 °C.