Extended Data Fig. 8: In vitro expansion of autologous T-cell clonotypes after stimulation with peptide antigens. | Nature Medicine

Extended Data Fig. 8: In vitro expansion of autologous T-cell clonotypes after stimulation with peptide antigens.

From: Tumor-infiltrating lymphocyte treatment for anti-PD-1-resistant metastatic lung cancer: a phase 1 trial

Extended Data Fig. 8

Clonotypes with significant increase using autologous T and dendritic cells from a, Patient 25 and b, Patient 9. T cells were co-cultured with autologous dendritic cells for 10 days and compared to controls wells including T cells only and no peptides. TCR Vβ CDR3 AA denotes T-cell receptor Vβ complementarity-determining region 3 amino acid. Fold expansion is relative to baseline control without peptide.

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