Extended Data Fig. 9: Expression of immune checkpoint ligands and cell composition of final infused TIL product.

a, Expression of immune checkpoint and cell activation markers assessed by flow cytometry as a proportion of either CD4⁺ or CD8⁺ T cells (n = 18 patients with 1 biologically independent experiment per patient, bar denotes median). b, Proportion of regulatory T cells (CD4⁺ CD25⁺CD127^dim). (n = 18 patients with 1 biologically independent experiment per patient). c, TIL cell population stratified by t-distributed stochastic neighbor embedding (t-SNE) mapping of memory differentiation subsets. Defined cell populations were assigned specific colors. Each patient is labeled by Pt ID. There are 18 patients presented in total, with 1 biologically independent experiment per patient.