Table 2 Performance of EXAM on independent datasets. Top, breakdown of patients by level of oxygen required across independent datasets from CDH, MVH and NCH. Bottom, AUC for prediction of the level of oxygen required at 24 and 72 h for the three independent datasets (95% confidence intervals)
From: Federated learning for predicting clinical outcomes in patients with COVID-19
Site | Cases (n) | Positive cases (n) | Prediction interval (h) | Patients at each level of oxygen requirement (n) | |||
|---|---|---|---|---|---|---|---|
RA | LFO | HFO-NV | MV and death | ||||
CDH | 840 | 244 | 24 | 608 | 162 | 48 | 22 |
72 | 575 | 173 | 62 | 30 | |||
MVH | 399 | 30 | 24 | 356 | 36 | 3 | 4 |
72 | 351 | 39 | 3 | 6 | |||
NCH | 264 | 29 | 24 | 237 | 23 | 4 | 0 |
72 | 235 | 22 | 4 | 3 | |||
Site | Prediction interval (h) | ≥LFO | ≥HFO-NV | ≥MV | Average AUC |
|---|---|---|---|---|---|
CDH | 24 | 0.925 (0.903, 0.945) | 0.950 (0.926, 0.971) | 0.956 (0.918, 0.984) | 0.944 |
72 | 0.902 (0.881, 0.924) | 0.931 (0.905, 0.955) | 0.938 (0.893, 0.927) | 0.924 | |
MVH | 24 | 0.904 (0.844, 0.954) | 0.836 (0.620, 0.978) | 0.964 (0.925, 1.000) | 0.901 |
72 | 0.887 (0.827, 0.940) | 0.872 (0.663, 0.992) | 0.988 (0.973, 0.997) | 0.916 | |
NCH | 24 | 0.895 (0.833, 0.950) | 0.984 (0.957, 1.000) | N/A | N/A |
72 | 0.904 (0.850, 0.949) | 0.947 (0.890, 0.991) | 0.931 (0.897, 0.959) | 0.927 |
