Extended Data Fig. 8.: Memory CD8 T cell subsets of patients with MS treated with aCD20 and healthy controls after SARS-CoV-2 mRNA vaccination.

Frequency of memory CD8 T cell subsets in total non-naive CD8 T cells. Left panels depict the percent of total non-naive T cells that are in each subset. Right panels depict the relative frequency of each memory T cell subset in the total non-naive population. CM = CD45RA⁻CD27⁺ CCR7⁺, EM1 = CD45RA⁻CD27⁺ CCR7⁻, EM2 = CD45RA⁻CD27⁻CCR7⁺, EM3 = CD45RA⁻CD27⁻CCR7⁻, EMRA = CD45RA⁺ CD27⁻CCR7⁻. Top panel: HCs (n = 10). Bottom panel: MS-aCD20 (n = 20).