Extended Data Fig. 8: Low Ct populations ≥14 days after second vaccination.

(a) Adjusted effects of vaccine type and months since second vaccination on probability of belonging to the low Ct sub-population; (b) adjusted effects of vaccine type and months since second vaccination on Ct values within the low Ct sub-population; (c) adjusted effects of calendar time on Ct values within the low Ct sub-population. Shaded areas represent 95% confidence intervals. Note: data include all new PCR positives among those ≥18 years old; estimated at the reference category for other factors (27 April 2021, male, no previous PCR/antibody-positive, not reporting a long-term health condition). In (c), test for non-linearity in effect of calendar date p = 0.003 for low and <0.0001 for high Ct sub-population (two-sided Wald test without adjustment for multiple comparison).