Extended Data Fig. 1: Clinical course and biochemical parameters after CAR-T cell treatment.
The time periods associated with cytokine release syndrome (CRS), neutropenic fever and neurotoxicity are annotated in the individual subplots. All cytokine levels were determined in the peripheral blood. (a) Temperature curve. (b) Administration of relevant pharmacologic treatments during the period after CAR-T treatment. (c) Total leukocyte, lymphocyte, and neutrophil counts. (d) Time course of CRP level (mg/L). (e) Time course of ferritin level (ng/mL). (f) Time course of IL-18 level (pg/mL). (g) Time course of IL-2Ra (CD25) level (pg/mL).
