Extended Data Fig. 2: Cytokine levels and time course after CAR-T cell treatment. | Nature Medicine

Extended Data Fig. 2: Cytokine levels and time course after CAR-T cell treatment.

From: Neurocognitive and hypokinetic movement disorder with features of parkinsonism after BCMA-targeting CAR-T cell therapy

Extended Data Fig. 2

The time periods associated with cytokine release syndrome (CRS), neutropenic fever and neurotoxicity are annotated in the individual subplots. (a) Time course of IFN-gamma level (pg/mL). (b) Time course of TNF-alpha level (pg/mL). (c) Time course of IL-6 level (pg/mL). (d) Time course of IL-10 level (pg/mL). All measurements are from peripheral blood plasma. (e) Olink cytokine profiling of peripheral blood plasma at different time points after chimeric antigen receptor (CAR) T cell therapy. Values shown are normalized protein expression (NPX) values according the Olink protocol in log2 scale (high protein levels in red, low protein levels in blue).

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