Extended Data Fig. 2: Antibody responses to the vaccine A(H3N2) strain, by age and prior A(H3N2) infection status and age group.
From: Influenza virus infection history shapes antibody responses to influenza vaccination
a, Titers against egg-grown A/Hong Kong/4801/2014 are plotted against participant age and prior infection status (color coded, legend) for the time points indicated. Linear regression lines are shown for each group with 95% confidence intervals. Pearsons correlation coefficients are shown with 2-sided p values. b, GMTs and c, GMRs are shown for participants stratified by prior infection and age group (color coded, legend) at the indicated time points. Symbols indicate mean values and error bars indicate 95% confidence intervals. Numbers per age group with no recent A(H3N2) are: 1935–59, n = 8; 1960–60, n = 9; 1970–79, n = 6; 1980–86, n = 5. Numbers per age group with recent A(H3N2) are: 1935–59, n = 16; 1960–60, n = 27; 1970–79, n = 21; 1980–86, n = 8. Horizontal lines indicate cut-offs for seropositivity or seroconversion.
