Extended Data Fig. 4: Differentially abundant taxa in patients who developed grade 3–4 adverse events (a) and those who did not develop grade 3–4 adverse events.

Differentially abundant taxa in patients who developed grade 3–4 adverse events (a) and those who did not develop grade 3-4 adverse events (b). Analyses were performed using n=52 stool samples from n=18 patients in nivolumab/ipilimumab with CBM588 arm and n=8 patients in nivolumab/ipilimumab arm). Two-sided Mann-Whitney U test used to compare species across two groups. The length of the box plots represents the interquartile range (IQR) and the inside lines of the boxes represent the median.